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Risk factors for chronic graft-versus-host disease after anti-thymocyte globulin-based haploidentical hematopoietic stem cell transplantation in acute myeloid leukemia

Meng Lv, Xiaohui Zhang, Lanping Xu, Yu Wang, Chenhua Yan, Huan Chen, Yuhong Chen, Wei Han, Fengrong Wang, Jingzhi Wang, Kaiyan Liu, Xiaojun Huang, Xiaodong Mo

《医学前沿（英文）》 2019年第13卷第6期页码 667-679 doi: 10.1007/s11684-019-0702-z

摘要： Chronic graft-versus-host disease (cGVHD) is a major complication following unmanipulated haploidentical hematopoietic stem cell transplantation (haplo-HSCT). We aimed to identify the risk factors for cGVHD in patients who underwent anti-thymocyte globulin-based haplo-HSCT for acute myeloid leukemia ( =280). The diagnosis of cGVHD was in accordance with the National Institutes of Health consensus criteria. A total of 169 patients suffered from cGVHD. The patients who had 3 loci mismatched had a higher 8-year incidence of cGVHD (total, 66.0% vs. 53.7%, =0.031; moderate to severe, 42.4% vs. 30.1%, =0.036) than the patients who had 1 to 2 loci mismatched. The patients who had maternal donors had a higher 8-year incidence of moderate to severe cGVHD (49.2% vs. 32.9%, =0.024) compared with the patients who had other donors. The patients who had grades III to IV acute GVHD (aGVHD) had higher 8-year incidence of cGVHD (total, 88.0% vs. 50.4%, <0.001; moderate to severe, 68.0% vs. 27.0%, <0.001) compared with the patients without aGVHD. In multivariate analysis, grades III to IV aGVHD was the only independent risk factor for cGVHD. Thus, further interventions should be considered in patients with severe aGVHD to prevent cGVHD.

关键词： acute graft-versus-host disease chronic graft-versus-host disease National Institutes of Health consensus criteria acute myeloid leukemia anti-thymocyte globulin

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基于犹豫模糊决策矩阵的犹豫模糊多准则共识群决策方法 Article

Jie DING, Ze-shui XU, Hu-chang LIAO

《信息与电子工程前沿（英文）》 2017年第18卷第11期页码 1679-1692 doi: 10.1631/FITEE.1601546

摘要：群决策在管理决策和经济领域有着重要作用。本文建立了两种关于犹豫模糊多准则群共识决策的方法，并使用犹豫模糊决策矩阵（hesitant fuzzy decision matrices, HFDMs）表示专家的偏好。本文建立了两个新颖的、可应用于不同群决策环境的共识模型，其中共识决策过程包括：共识检验过程，共识达成过程和选择过程。专家以犹豫模糊集的方式表达自己的选择，然后通过集成算子计算每个准则下的犹豫模糊集。此外，基于两个专家在决策之间的偏差计算出任意两个犹豫模糊集之间的距离。本文建立了两种达成共识的方法，并提出了两种犹豫模糊多准则群决策方法的具体计算步骤。最后通过具体案例分析了苹果公司以旧换新的决策过程。该案例旨在让所有专家在进行选择决策之前达成高度共识，避免一些专家的偏好值过高或过低。通过共识测量修正的偏好信息可令决策结果更加合理。

关键词：多准则群决策；群共识；共识达成方法；犹豫模糊决策矩阵；集成算子

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Human health ambient water quality criteria for 13 heavy metals and health risk assessment in Taihu Lake

《环境科学与工程前沿（英文）》 2022年第16卷第4期 doi: 10.1007/s11783-021-1475-6

摘要：

• The concentrations of 13 heavy metals in Taihu Lake were analyzed.

关键词： Heavy metals Human health ambient water quality criteria Taihu Lake Health risk assessment Contribution rate

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A step forward in laparoscopic hepatectomy: comments on “Expert Consensus on Laparoscopic Hepatectomy(2013 Version) by National Hepatic Surgery Group, Society of Surgery, Chinese Medical Association”

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《医学前沿（英文）》 2013年第7卷第4期页码 520-522 doi: 10.1007/s11684-013-0302-2

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全民健康与医药卫生事业发展战略研究

王小宁,付磊,尹岭,支晨,李晓雪,刘晓云,尹德卢,王健,刘冉,党海霞,刘运芳,杨志平,王陇德,樊代明

《中国工程科学》 2017年第19卷第2期页码 1-7 doi: 10.15302/J-SSCAE-2017.02.001

摘要：

2014年6月，中国工程院启动了“我国全民健康与医药卫生事业发展战略研究”重大咨询项目，深入分析了制约我国全民健康与医药卫生事业发展的瓶颈问题，提出了相应的对策建议，并形成研究报告。在此基础上，项目组结合新近动态，特别是党中央和国务院在“全国卫生与健康大会”上的指示精神，对若干问题做进一步论述。面对全民健康日益恶化的严峻形势和人民群众“看病难，看病贵”的难题，本文强调应把我国医药卫生事业的重心从疾病救治模式向防控模式转移，同时尽快调整全民健康和医药卫生事业的统领模式，加强政府引导，强化公民健康促进的国家意识和制度建设，使每个公民都能自觉地参与到健康促进的行动中来，确保全民健康促进与医药卫生事业发展新策略的高效落地，从而实现长久可持续发展。

关键词：全民健康医药卫生发展战略

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Contribution of national bioassessment approaches for assessing ecological water security: an AUSRIVAS

Susan J. NICHOLS, Fiona J. DYER

《环境科学与工程前沿（英文）》 2013年第7卷第5期页码 669-687 doi: 10.1007/s11783-013-0556-6

摘要： River managers in Australia are managing in the face of extremes to provide security of water supply for people, production and the environment. Balancing the water requirements of people, environments and economies requires that water security is viewed holistically, not just in terms of the water available for human consumption. Common definitions of water security focus on the needs of both humans and ecosystems for purposes such as drinking, agriculture and industrial use, and to maintain ecological values. Information about achieving water security for the environment or ecological purposes can be a challenge to interpret because the watering requirements of key ecological processes or assets are not well understood, and the links between ecological and human values are often not obvious to water users. Yet the concepts surrounding river health are inherently linked to holistic concepts of water security. The measurement of aquatic biota provides a valuable tool for managers to understand progress toward achieving ecological water security objectives. This paper provides a comprehensive review of the reference condition approach to river health assessment, using the development of the Australian River Assessment System (AUSRIVAS) as a case study. We make the link between the biological assessment of river health and assessment of ecological water security, and suggest that such an approach provides a way of reporting that is relevant to the contribution made by ecosystems to water security. The reference condition approach, which is the condition representative of minimally disturbed sites organized by selected physical, chemical, and biological characteristics, is most important for assessing ecological water security objectives.

关键词： ecological water security biological assessment river health

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全民健康和医药卫生教育及法规体系研究

刘晓云,常春,侯建林,杨健,田传胜,纪颖,胡丹,孟庆跃,王陇德

《中国工程科学》 2017年第19卷第2期页码 50-54 doi: 10.15302/J-SSCAE-2017.02.008

摘要：

我国医药卫生体制改革取得重大进展，但在全民健康教育、卫生人才培养及卫生法律体系建设等方面仍存在巨大挑战。本文总结国内外已有经验，分析我国全民健康和医药卫生教育及法规体系现状和面临的挑战，提出了完善全民健康和医药卫生教育及法规体系的政策建议：构建全民健康教育体系，加强全民健康教育的强制性；根据社会需求培养适宜卫生人才，加强全科医生培养，提高基层医疗卫生服务水平和可及性；尽快推动医药卫生“母法”的出台，并对现行医药卫生相关的法律、规章和规范性文件进行梳理和修订。

关键词：全民健康健康教育医学教育卫生法律

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制造业的未来——一个新视角 Perspective

Ben Wang

《工程（英文）》 2018年第4卷第5期页码 722-728 doi: 10.1016/j.eng.2018.07.020

摘要：

关于智能制造，前人已发表了很多文章。其大多数内容都集中在硬件、软件、增材制造、机器人、物联网（Internet of Thing，IoT）以及工业4.0 等话题，而对另一些极重要的领域却少有讨论，如混合系统、先进制造业重定义、新制造的基本构成元素、制造业生态系统准备水平及技术可扩展性等。本文将通过实例，从全新的视角，为读者剖析这些领域中目前的四个挑战。挑战一：当我们希望提高公众对新制造业经济及其社会影响的认识水平，并获得政策制定者的明确支持时，应如何重新定义未来制造业。挑战二：如何正确认识到未来制造业的关键词是“混合”。它具有人类与机器人协作、增材制造与减材制造结合、金属材料与复合材料并用以及网络系统与物理系统融合等特点。因此，划定界限与制定标准变得尤其重要。挑战三：如何开发一个同时对技术、制造商业化和新制造生态系统做出评估的通用框架，以缩短生产到交付之间的时间；以及在该框架下，如何进一步制定一套可被广泛采用的、针对非信息技术的可扩增性测量的标准。最后，也是同样重要的是挑战四：如何通过公司多方合作，来验证“产- 学- 政”三位一体的模型是否成功。本文将详细讨论上述四大挑战。

关键词：先进制造伙伴计划制造业生态系统工业4.0 智能制造物联网制造业创新研究院美国国家制造创新网络

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Emergence mechanisms of group consensus in social networks

《工程管理前沿（英文）》 doi: 10.1007/s42524-023-0277-x

摘要： Reaching consensus within larger social network groups has emerged as a pivotal concern in the digital age of connectivity. This article redefines group consensus as the emergence of collective intelligence resulting from self-organizing actions and interactions of individuals within a social network group. In our exploration of extant research on group consensus, we illuminate two frequently underestimated, yet noteworthy facets: Dynamism and emergence. In contrast to the conventional perspective of consensus as a mere outcome, we perceive it as an ongoing, dynamic process. This process encompasses self-organized communication and interaction among group members, collectively guiding the group towards cognitive convergence and viewpoint integration. Consequently, it is imperative to redirect our focus from the outcomes of group interactions to an examination of the relationships and processes underpinning consensus formation, thus elucidating the mechanisms responsible for the generation of group consensus. The amalgamation of cognitive contexts and accurate simplification of real-world scenarios for simulation and experimental analysis offers a pragmatic operational approach. This study contributes novel theoretical underpinnings and quantitative insights for establishing and sustaining group consensus within the realm of engineering management practices. Concurrently, it holds substantial importance for advancing the broader research landscape pertaining to social consensus.

关键词： group consensus social network collective intelligence

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我国国境生物安全防控体系现代化建设研究

徐建国,舒跃龙,易在炯,田桢干,李振军,王小理,沈洪兵,何宇平

《中国工程科学》 2023年第25卷第5期页码 21-29 doi: 10.15302/J-SSCAE-2023.05.001

摘要： The new US national biodefense strategy-necessary but not sufficient [J]‍.JAMA Health Forum , 2022 , 3 12 : e225206 ‍.">4]。BMC Public Health , 2011 , 11 2 : S2 ‍.US Centers for Disease Control and Prevention and its partners´ contributions to global healthHis major research field is development of public health capacities at points of entry/exit.

关键词：生物安全；公共卫生；国境口岸；传染病防控；卫生检疫

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Finite element analysis of stress concentrations and failure criteria in composite plates with circular

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《机械工程前沿（英文）》 2014年第9卷第3期页码 281-294 doi: 10.1007/s11465-014-0307-9

摘要：

In this study, the stress concentration factors (SCF) in cross-and-angle-ply laminated composite plates as well as in isotropic plates with single circular holes subjected to uniaxial loading is studied. A quadrilateral finite element of four-node with 32 degrees of freedom at each node, previously developed for the bending and mechanical buckling of laminated composite plates, is used to evaluate the stress distribution in laminated composite plates with central circular holes. Based up on the classical plate theory, the present finite element is a combination of a linear isoparametric membrane element and a high precision rectangular Hermitian element. The numerical results obtained by the present element compare favorably with those obtained by the analytic approaches published in literature. It is observed that the obtained results are very close to the reference results, which demonstrates the accuracy of the present element. Additionally, to determine the first ply failure (FPF) of laminated plate, several failure criterions are employed. Finally, to show the effect of ratio on the failure of plates, a number of figures are given for different fiber orientation angles.

关键词： laminated composite plates stress concentration geometric singularity anisotropic effect

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Trapezoidal Intuitionistic Fuzzy Aggregation Operator Based on Choquet Integral and Its Application to Multi-Criteria

Xi-hua Li,Xiao-hong Chen

《工程管理前沿（英文）》 2015年第2卷第3期页码 266-276 doi: 10.15302/J-FEM-2015048

摘要： The Choquet integral can serve as a useful tool to aggregate interacting criteria in an uncertain environment. In this paper, a trapezoidal intuitionistic fuzzy aggregation operator based on the Choquet integral is proposed for multi-criteria decision-making problems. The decision information takes the form of trapezoidal intuitionistic fuzzy numbers and both the importance and the interaction information among decision-making criteria are considered. On the basis of the introduction of trapezoidal intuitionistic fuzzy numbers, its operational laws and expected value are defined. A trapezoidal intuitionistic fuzzy aggregation operator based on the Choquet integral is then defined and some of its properties are investigated. A new multi-criteria decision-making method based on a trapezoidal intuitionistic fuzzy Choquet integral operator is proposed. Finally, an illustrative example is used to show the feasibility and availability of the proposed method.

关键词： multi-criteria decision making trapezoidal intuitionistic fuzzy numbers Choquet integral fuzzy measure aggregation operator

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Cost-benefit analysis of China’s national air pollution control plan

Jing ZHANG, Hongqiang JIANG, Wei ZHANG, Guoxia MA, Yanchao WANG, Yaling LU, Xi HU, Jia ZHOU, Fei PENG, Jun BI, Jinnan WANG

《工程管理前沿（英文）》 2019年第6卷第4期页码 524-537 doi: 10.1007/s42524-019-0074-8

摘要： China’s rapid economic growth has caused severe air pollution and public health problems. Therefore, the Chinese government launched the National Air Pollution Control Plan (hereinafter referred to as the “Air Plan”) in 2013–2017 to improve air quality and safeguard public health. In this study, an analytical framework for a cost-benefit analysis applicable to China was constructed, and the costs and benefits of the implementation of the “Air Plan” in 30 cities and provinces in China from 2013 to 2017 were evaluated. Results show that the total cost of implementation of the “Air Plan” is 1.6511 trillion RMB. The benefits of air quality improvement were determined to be 2.4691 trillion RMB through the willingness-to-pay method to calculate the economic loss of premature deaths. The net benefit related to the implementation of the “Air Plan” was 818 billion RMB. The public health benefit of air quality improvement was 1.5 times the cost of the nationwide implementation of the “Air Plan”. At the provincial level, net benefits that reach 279.3 billion RMB were the highest in Guangdong, whereas the benefit-cost ratio, where the benefit was 5.5 times the cost, was the highest in Fujian. Estimations in this study can serve as a reference for China in formulating similar environmental policies and implementing the “3-year Plan to Defend the Blue Sky”. In addition, these estimations have practical significance for advancing the long-term effective mechanisms of the cost-benefit analysis of China’s environmental policies.

关键词： Air Plan cost-benefit analysis health benefits environmental policy

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Concepts and implementation of strain-based criteria in design codes for steel structures

Reidar BJORHOVDE

《结构与土木工程前沿（英文）》 2012年第6卷第3期页码 210-216 doi: 10.1007/s11709-012-0165-7

摘要： A uniaxial tension test is commonly used to determine the mechanical properties of steel, but it has no meaning for the response of the material in a structure. The test was developed as a consensus solution by producers, fabricators, designers and code writers, to have a standard by which similar materials could be compared to a common base. It does not represent the actual behavior of the steel in a structure, and was never intended to do so. To study the true behavior of the structure and how the material responds it would be better to determine the strains and deformations that will take place during actual service condition. Such characteristics reflect the real behavior, whether in the elastic or inelastic range. If stresses or forces are needed, these are easily determined by the value of the strain and the relevant material modulus, along with the type of cross section, whether elastic or inelastic. The paper addresses the properties of a range of structural steels, how these are incorporated into design standards and how the standards define deformation characteristics and demands for bolted and welded connections.

关键词： steel stress-strain characteristics tension test strain design actual behavior improved design codes

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LSSVM-based approach for refining soil failure criteria and calculating safety factor of slopes

Shiguo XIAO; Shaohong LI

《结构与土木工程前沿（英文）》 2022年第16卷第7期页码 871-881 doi: 10.1007/s11709-022-0863-8

摘要： The failure criteria of practical soil mass are very complex, and have significant influence on the safety factor of slope stability. The Coulomb strength criterion and the power-law failure criterion are classically simplified. Each one has limited applicability owing to the noticeable difference between calculated predictions and actual results in some cases. In the work reported here, an analysis method based on the least square support vector machine (LSSVM), a machine learning model, is purposefully provided to establish a complex nonlinear failure criterion via iteration computation based on strength test data of the soil, which is of more extensive applicability to many problems of slope stability. In particular, three evaluation indexes including coefficient of determination, mean absolute percentage error, and mean square error indicate that fitting precision of the machine learning-based failure criterion is better than those of the linear Coulomb criterion and nonlinear power-law criterion. Based on the proposed LSSVM approach to determine the failure criterion, the limit equilibrium method can be used to calculate the safety factor of three-dimensional slope stability. Analysis of results of the safety factor of two three-dimensional homogeneous slopes shows that the maximum relative errors between the proposed approach and the linear failure criterion-based method and the power-law failure criterion-based method are about 12% and 7%, respectively.

关键词： slope stability safety factor failure criterion least square support vector machine

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标题作者时间类型操作

Risk factors for chronic graft-versus-host disease after anti-thymocyte globulin-based haploidentical hematopoietic stem cell transplantation in acute myeloid leukemia

Meng Lv, Xiaohui Zhang, Lanping Xu, Yu Wang, Chenhua Yan, Huan Chen, Yuhong Chen, Wei Han, Fengrong Wang, Jingzhi Wang, Kaiyan Liu, Xiaojun Huang, Xiaodong Mo

期刊论文

基于犹豫模糊决策矩阵的犹豫模糊多准则共识群决策方法

Jie DING, Ze-shui XU, Hu-chang LIAO

期刊论文

Human health ambient water quality criteria for 13 heavy metals and health risk assessment in Taihu Lake

期刊论文

null

期刊论文

全民健康与医药卫生事业发展战略研究

王小宁,付磊,尹岭,支晨,李晓雪,刘晓云,尹德卢,王健,刘冉,党海霞,刘运芳,杨志平,王陇德,樊代明

期刊论文

Contribution of national bioassessment approaches for assessing ecological water security: an AUSRIVAS